IM Browser Getting Started


1. First, we will build a map of interactions involving members of the Skp family of proteins.

From the main menu select 'Edit'->'Add Gene/Protein'.

Alternatively, from the main menu select 'File'->'New graph'



The query form has two steps.

Step 1 is to find your gene or protein of interest in a look-up table.

Click on the button “Select genes/proteins from a lookup table”.



A new dialog box will appear.

In the pull-down menu select “Symbol”.

In the text area enter 'skp*'.

Note: Be sure to use the wild card '*' to find all of the Skp genes.



IM Browser will display a list of genes that satisfy your search criteria.

Select the genes of interest either by clicking on "Select All" or by clicking on check boxes.

Click “OK”.



Now we are back to the query form.

The IDs of the selected genes were added to the text area.

You can conduct additional searches and the new IDs will be added to the text area.

In step 2 you select the interaction tables to search.

Click OK.



The resulting graph consists of the interactions of Skp family genes found in tables "Curagen YTH", "Hybrigenics YTH" and "Finley YTH".


NEXT SLIDE


We appreciate your feedback. Please send comments or concerns about IM Browser to Lana Pacifico: lpacifico(at)wayne.edu.